National Center for Structural Biology and Bioimaging (CENABIO)
The National Center for Structural Biology and Bioimaging (CENABIO) is a multiuser facility of the Federal University of Rio de Janeiro (UFRJ) where studies and experimental approaches are carried out to obtain images of organs, cells and biomolecules. It has state-of-the-art equipment, experienced technical staff and its board of directors is composed of highly qualified researchers and professors.
CENABIO’s Structural Biology Unit was originally founded in 1998 as the National Center of Macromolecular Nuclear Magnetic Resonance (CNRMN). It is currently the only facility in Brazil with a unique set of equipment dedicated to the structure and dynamics of proteins and other biomolecules.
In 2009, CENABIO received the support of the National Institutes of Science and Technology (INCT-INBEB). In this same year, it was granted resources to build a small-animal bioimaging facility that offers the following techniques: luminescence, fluorescence, ultrasound, PET-SPECT-CT and a small-animal nuclear magnetic resonance spectrometer. Thus, in May 2010, CENABIO’s Small-Animal Imaging Unit was born.
When the Advanced Microscopy Unit was built it expanded the already solid multiuser structure available. It is recognized as the most complete microscopy facility in Latin America, in which the following microscopy techniques are available: confocal, super-resolution, multi-photon, TIRF, optical tweezers, atomic force, scanning electron microscopy, high-resolution scanning electron microscopy with cryostage and FIB/SEM system, transmission electron microscopy, analytical transmission electron microscopy using X-ray emission spectrum, transmission electron microscopy operating at 200 KV with cryostage, and an automated cryoelectron tomography system.
Finally, CENABIO has a Protein Advanced Biochemistry platform highly specialized in services of production and analysis of proteins and peptides.
In addition to INCT-INBEB, CENABIO anchors the recently created INCT in Regenerative Medicine (INCT-Regenera), which is based on the triad (includes) of stem cells, matrices, and recombinant factors for research on bioengineering of organs and tissues.
MEET OUR UNITS
Protein Advanced Biochemistry – PAB
